Skip to main content
All topics
Cyber Security

Microsoft Defender for Office 365

Microsoft Defender for Office 365 (formerly Office 365 ATP) is Microsoft's advanced email and collaboration security platform, designed to protect Microsoft 365 environments from phishing, malware, ransomware, and business email compromise. While Exchange Online Protection provides basic anti-spam and anti-malware, Defender for Office 365 adds advanced threat protection — safe links, safe attachments, anti-phishing, and threat hunting capabilities. For UK businesses using Microsoft 365, Defender for Office 365 is a critical layer of security that protects against the email-based attacks that cause the majority of security incidents. We help businesses across London and the UK deploy, configure, and manage Microsoft Defender for Office 365 — ensuring your email and collaboration tools are protected against the full spectrum of modern threats.

The short answer

Microsoft Defender for Office 365 is an advanced email and collaboration security platform that protects against phishing, malware, ransomware, and business email compromise. It includes Safe Links (URL rewriting and scanning), Safe Attachments (sandbox detonation of email attachments), Anti-phishing policies (impersonation protection), Threat Explorer (threat hunting and investigation), and Automated Investigation and Response (automated remediation). It is available in Plan 1 (included with Business Premium and E3) and Plan 2 (included with E5) tiers.

Enable Safe Links and Safe Attachments for all users — these are the most effective protections against email-based threats.
Configure anti-phishing policies with impersonation protection for your executives and key staff.
Set up alert policies for suspicious activity and regularly review alerts.
Use Threat Explorer to investigate threats and identify targeted attacks.
What Is It?

Understanding Microsoft Defender for Office 365

Microsoft Defender for Office 365 is an advanced email and collaboration security platform that protects against phishing, malware, ransomware, and business email compromise. It includes Safe Links (URL rewriting and scanning), Safe Attachments (sandbox detonation of email attachments), Anti-phishing policies (impersonation protection), Threat Explorer (threat hunting and investigation), and Automated Investigation and Response (automated remediation). It is available in Plan 1 (included with Business Premium and E3) and Plan 2 (included with E5) tiers.

Why It Matters

The business impact

Email is the #1 attack vector for cybercriminals, with over 90% of security incidents starting with a phishing email. While Exchange Online Protection blocks most spam and known malware, it cannot detect sophisticated, targeted attacks like zero-day malware, spear-phishing, and business email compromise. Defender for Office 365 adds the advanced detection capabilities needed to stop these threats — protecting your business from the email-based attacks that cause the most damage.

Who needs this?

Any business using Microsoft 365 that needs advanced email security beyond basic anti-spam. Businesses that handle sensitive communications or financial transactions via email. Businesses that are concerned about phishing, ransomware, or business email compromise. Businesses that need to meet compliance requirements for email security. Businesses that want automated threat detection and response rather than manual investigation.

Who doesn't need this?

Businesses already using Mimecast or a similar enterprise email security solution may not need Defender for Office 365 — though some businesses use both for layered protection. Very small businesses (1–5 users) with low risk may find Exchange Online Protection sufficient, though we recommend at least basic Defender for Office 365 for all businesses.

How It Works

The technical overview

Defender for Office 365 sits within the Microsoft 365 environment, scanning all inbound, outbound, and internal email. Safe Links rewrites URLs in email and checks them at click time. Safe Attachments opens email attachments in a sandbox environment to detect malicious behaviour before delivery. Anti-phishing policies detect impersonation attempts. Threat Explorer provides real-time visibility into threats. Automated Investigation and Response can automatically remediate threats without admin intervention.

Technologies & Entities

Related technologies

Microsoft Defender for Office 365 Exchange Online Protection Microsoft 365 Microsoft Defender for Endpoint Microsoft Sentinel Entra ID Microsoft Purview
Pricing Factors

What affects the cost?

Included with Business Premium
Defender for Office 365 Plan 1 is included with Microsoft 365 Business Premium at no additional cost.
Standalone Plan 1
Defender for Office 365 Plan 1 costs approximately £3.90 per user per month as a standalone add-on.
Plan 2
Defender for Office 365 Plan 2 adds automated investigation and response, and costs approximately £7.10 per user per month.
Setup and configuration
Defender for Office 365 setup and policy configuration typically costs £500–£2,000 depending on complexity.
Best Practices

Expert recommendations

Enable Safe Links and Safe Attachments for all users — these are the most effective protections against email-based threats.

Configure anti-phishing policies with impersonation protection for your executives and key staff.

Set up alert policies for suspicious activity and regularly review alerts.

Use Threat Explorer to investigate threats and identify targeted attacks.

Train users to report suspicious emails using the Report Message button in Outlook.

Regularly review and tune policies based on threat trends and false positive rates.

Industries

Industries that benefit

All industriesFinancial servicesLegalHealthcareProfessional servicesConstructionRetail

Need help with microsoft defender for office 365?

Our certified engineers can help you evaluate, deploy, and manage microsoft defender for office 365 for your business.

FAQ

Microsoft Defender for Office 365 — your questions answered

Common questions about microsoft defender for office 365, pricing, implementation, and best practices.

Ready when you are

Book your free consultation in 30 seconds.

No obligation. No spam. Just a certified engineer with a clear, proactive roadmap.

Response <60 min
Certified & insured
SLA-backed
No surprise fees